Objective: Muscular dystrophy is a genetic disease and associated with progressive muscle wasting and weakness.
Impaired muscle strength may be associated with nutritional insufficiency in patients with muscular dystrophy.
Morbidity and mortality may be also influenced by poor diet in these patients. Therefore, it is needed to assess
nutritional intake as well as formulation of healthy, balanced-diet for dystrophy patients.
Methods: Oxidative-stress based degeneration is the major cause of muscle wasting in patients with muscular
dystrophy. Formulation of the diet is based on the protection against oxidative-stress in patients with muscular
dystrophy. The diet was given to patients with muscular dystrophy and SOD (Superoxide dismutase), GPx
(glutathione peroxidase), CAT (catalase) and LP (lipid peroxidation) was measured in serum. The level of all these
parameters was measured in serum of patients with muscular dystrophy vs. control subjects, patients with two months
medicinal treatment vs. non-medicinal treatment, and patients with medicinal treatment and formulated diet
consumption vs. patients with medicinal treatment after two & four months duration. The muscle power was also
determined in patients with medicinal treatment and formulated diet consumption vs. patients with medicinal
treatment after two & four month duration.
Results: Level of SOD, GPx, CAT and LP was higher in patients with muscular dystrophy as compared to control
subjects. No soma online significant difference was observed in the level of these parameters in patients with two months
medicinal treatment vs. non-medicinal treatment. There was a significant difference observed for all these
parameters in the serum of patients with medicinal treatment and formulated diet consumption vs. medicinal
treatment after two and four month’s duration. Grading of muscle power showed the difference in patients with
medicinal treatment and formulated diet consumption vs. patients with medicinal treatment after two &
four month’s duration. But, these differences do not approach the significant.
Discussion: The formulated diet chart might prove helpful for better management of muscular dystrophy. It is a
well-known fact that genetic diseases are not curable. Available medications temporary delay the deterioration in
patients with muscular dystrophy.
