Epidemiological studies have shown a positive correlation between osteoporosis/osteopenia (OOS) and coronary artery disease (CAD). Here we aimed to study the prevalence of OOS in patients with CAD in lorestan. We performed a cross sectional study on 160 randomly selected patients with coronary artery disease from Khorammabad Heart center affiliated with Lorestan University of medical science. The study was performed fromDesember2011 to May2012. All the patients had more than 50% stenosis of at least one of the coronary arteries. There were 78 (47%) female, 38 (22%) patients with diabtes, 78 (47%) with hypertension, 51 (30.7%) hperlipidemia and 41 (24.7%) of them were smokers. The prevalence of osteopenia was 45.2%, the prevalence of osteoporosis was 31.9% and 22.9% of the patients had normal BMD. In conclusion we showed the high prevalence of OOS among patients with CAD. This finding paves the way for future studies regarding OOS and CAD.