Objectives: The study aimed to identify the phytochemical constituents present in the leaves of Syzygium cumini (Myrtaceae) using the following solvents with various polarity: distilled water (aqueous), ethanol, methanol, ethyl acetate, and hexane. Methodology: The leaves were cleaned, air-dried, and ground to a coarse powder. The powders were divided into five and were soaked separately using distilled water, ethanol, methanol, ethyl acetate, and hexane for around one (1) week prior to phytochemical screening. Results: The study showed that both the ethanolic and methanolic extracts contained most of the phytochemical constituents, followed by the ethyl acetate, hexane, and aqueous extracts, respectively. These phytochemicals in the leaves include alkaloids; flavonoids; saponins; tannins; glycosides; phenols; proteins; triterpenoids; steroids; and fixed oils and fats, having proteins as the highest amount in all the five solvents. Conclusion: S. cumini leaves contain significant bioactive compounds that make the plant a potential antioxidant, anti-diabetic, and among other therapeutic uses.