A simple and reliable Gas chromatography-Mass spectrometer method was developed for the determination of Benzyl alcohol in injectable suspension. Methanol was used for extraction solvent and co-extractive was removed by filtrated through anhydrous sodium sulfate. The method was validated by determining parameters such as, specificity, linearity, limit of detection, limit of quantitation, precision, recovery and robustness. The method was found to be specific against matrix interferences. Linearity was evaluated over the concentration ranges of 0.1 μg/ml to 10 μg/ml and correlation coefficient was more than 0.999. Both the inter day and intra day precision of the system and method were determined. Recovery data obtained by fortifying three matrices at 0.5 μg/g, 1.0 μg/g and 2.0 μg/g with ranged between 98 to 105 % and the relative standard deviation (RSD) was obtained below 5%. Limit of detection and quantitation of Benzyl alcohol were 0.05 and 0.1 μg/g.
