Resistance to antibiotics has been noted in all species of streptococci however it varies from country to country. The goal of the present study was to get the knowledge about the epidemiology and chemotherapy of Streptococcal Group B, C and G as emerging pathogens. In this study 28 beta hemolytic streptococci were isolated from various clinical specimens from the hospitals and pathological laboratories of Karachi, Pakistan from November 2013 to October 2014. Among the collected strains we identified 18 (64%) GBS, 8 (29%) GGS and 2 (7%) GCS. Most of the GBS and GGS strains were isolated during the rainy season of the year and the majority of the strains were collected from throat swabs. Kibry-Bauer disc diffusion method and MIC analysis indicated that the strains of GGS were comparatively more resistant to various antibiotics as compared to GBS. GGS strains were 50% resistant to most macrolide antibiotics. Furthermore, these strains were also 39% resistant to clindamycin and 25% to penicillin, cefotaxime and ciprofloxacin. Among GBS the highest rate of resistance was observed against clarithromycin (43%), followed by azithromycin, erythromycin and clindamycin (39%). GCS strains were sensitive to all the antibiotics except being 50% clindamycin resistant. However all the strains in this study were sensitive to augmentin antibiotic. MIC analysis indicated that both GBS and GGS strains had the highest MIC against clindamycin. The findings of the present study would provide awareness about the epidemiology and chemotherapy of group B, C and G as the emerging pathogens among from our region.
