A Prospective cross-sectional study was carried out in order to assess the prescription pattern in pregnancy women’s. The stydy subjects were 200 pregnancy women from ante natal clinic at Coimbatore. Prescription pattern and qualification of antenatal care providers are assessed by using Instate Excel sheet. The main outcome measures were Calcium, Iron, and Folic acid are the main drug of choice .During pregnancy, either alone or in combination with other drugs. Self medication was more in higher socio economic and knowledge on contraceptive methods are less in rural population. Mean age of the group under the study was 28 years(range 25 to 30 years). The majority of Pregnancy women in Urban were house wife 56% (n=112) and no one is from Army, air force, Smoking and alcohol. Folic acid is mostly Prescribed in the Pregnancy prescriptions 21%(n=42) and Calcium and Iron were Prescribed in 21.5%(n=42) and 20%(n=40). The study resulted that Prescriber must encouraged to adhere to the standard guidelines like FDA- safety drugs for better ante- natal Care.