Research Article
Interactions between Acetaminophen and Phytotherapies: Overview for the Rational Use of Phytotherapics
Author(s): Juliana Silva Ribeiro, Juan Aitken Saavedra, Larissa Torres Nunes, Juliano Kilinski Tavares, Kaio Heide Sampaio Nóbrega and Rafael Guerra Lund*
Paracetamol is the most used non-opioid analgesic in the world, and it is used to relieve mild to moderate pain. On the other hand, phytotherapy is the use of plants or herbal supplements with known pharmacological effects. It is common for patients to use phytotherapy in conjunction with conventional drugs. Drug interactions are pharmacological responses in which the effects of one or more medicinal products are altered by their joint administration. The objective of this study is to evaluate the interaction between phytotherapics and paracetamol when administered together. Methods: The protocol of this review was registered in the PROSPERO/ CRD42018100106 international database for systematic reviews. The research question for this study was: Is there an interaction between phytotherapics and paracetamol when given together? Six databases were screened: PubMed (Medline); Lilacs; Ibe.. Read More»
