Review Article
The rs2241766, rs266729 and rs1501299 Polymorphisms in ADIPOQ Gene Play Substantial Role in Predisposition to Diabetes
Author(s): Md Murad Hossain* and Mithu Howlader
One of the most frequent non-communicable diseases in the world is Diabetes Mellitus (DM). Diabetes mellitus affects one out of every eleven
persons worldwide (90 percent having type 2 diabetes mellitus). Adiponectin is the most common peptide secreted by adipocytes, and its
decline is linked to obesity-related disorders such as insulin resistance, diabetes mellitus, and heart disease. Single Nucleotide Polymorphisms
(SNPs) in the adiponectin gene (ADIPOQ) have been linked to diabetes in several meta-analysis studies. The ADIPOQ gene's rs2241766,
rs266729 and rs1501299 polymorphisms have been identified as the most prevalent SNPs linked to the development of DM across the formats.
Despite the fact that all three SNPs are heavily correlated to DM, two common SNPs rs2241766 and rs266729 are linked to Type 1 Diabetes
Mellitus (T1DM), T.. Read More»
DOI:
10.37532/0975-5071-22.14.06
