By Raj K. Keservani, Narendra Vyas and Sarang Jain
Microneedles are expected to be less painful than conventional hypodermic needles because they are too small to significantly stimulate nerve endings. Small-scale studies so far have confirmed that expectation, and additional pain studies are planned. The safety and effectiveness of microneedles must still be proven in humans before they can receive Food & Drug Administration approval for clinical use. The broad range of sizes, shapes and materials will permit production of microneedle arrays customized for the type and volume of drug to be delivered, the time period of use, and most importantly, minimizing pain.
Key Words : Microneedles, hollow microneedles, coated microneedles, drug delivery.
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