Synthesis of Macrocyclic Schiff Bases with Vanadium(V) Complexes and their Antibacterial and Antioxidant Properties

By Vatsala Pawar,  Sunil joshi and V.Uma 

ABSTRACT

Macrocyclic Schiff bases were synthesized and evaluated for their antibacterial activities against various bacteria and also for their antioxidant effects in vitro by nitric acid free radical scavanging assay. Ligands TSCB and HDCB were obtained by the condensation of the Benzil with Thiosemicarbazide and Hydrazine dihydrochloride respectively in ethanolic medium. Further their vanadium complexes were prepared by condensing synthesized ligands with vanadium salt. The synthesized compounds were characterized using IR, 1H- NMR, UV spectral datas together with elemental analysis, MP, TLC, MW, conductivities determinations. 

Keywords: Macrocyclic ligands, Antioxidant Properties, Antibacterial Activities

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