Synthesis and study of antimicrobial agent 3-(3-substituted-1H-indon-1-yl)-2-phenylquinoline-4-carboxylic acid
By Anees A. Siddiqi, Jaya Dwivedi, Swapnil Sharma and Rajani Chauhan
Present work describes the Synthesis of 3-(3-substituted-1H-indon-1-yl)-2-phenylquinoline-4-carboxylic acid derivatives by Pfitzinger reaction of isatin with 2(1H-indol-1-yl)-1-phenyl ethanone and 1-phenyl-2-[-3-(substituted)-1H-indole-1-yl] ethanone. The structures of all the compounds are established by elemental analysis, IR, 1H NMR and Mass spectral data. These compounds possess excellent antimicrobial activity against bacteria and fungi.
Chalcone, Schiff’s base chalcone, quinazoline derivatives, antimicrobial activities.
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