By Devender Pathak, Nadeem Siddiqui, Bhanupriya Bhrigua, Waquar Ahsanb, M. Shamsher Alam
Benzimidazole and its derivatives are used in organic synthesis and they are used in evaluating
new product that possesses different biological activities. This review article covers the most
active benzimidazole derivatives that have shown considerable biological actions such as
antimicrobial, anti-inflammatory, anticancer, anticonvulsant, antidepressant, antioxidant,
radioprotective and anti-leishmanial. This review also discusses the structure-activity
relationship of the most potent compounds. It can act as an important tool for medicinal chemists
to develop newer compounds possessing benzimidazole moiety that could be better agents in
terms of efficacy and safety.
Key Words : Benzimidazoles, synthesis, biological activities.
Click here to download the complete article in PDF Format