Neuropharmacological screening of aerial parts of Passiflora incarnata Linn (Passifloraceae)

By Chitra V, Gowri K, Tamilanban T, Soni D.

Abstract

Methanolic extract of aerial parts of Passiflora incarnata Linn (Passifloraceae) was investigated for anxiolytic and antioxidant activities in animal models. Anxiolytic activity of methanol extract of aerial parts of Passiflora incarnata Linn was tested by Forced swimming test .The results showed a significant anxiolytic effect comparable,with diazepam in all the  tested doses. Passiflora incarnata Linn is also showing antioxidant activity by histopathology and biochemical parameter. In Histopathology slides of Methanolic extract of aerial parts of Passiflora incarnata treated groups’ shows prevention of degeneration of pyramidal cells, astrocytes and also shows collaterals when compared to control groups.

 

Key Words : Passiflora incarnata,Chronic Anti--anxiety, Antioxidant, Acetylcholinesterase

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